To fill out the GeneDx Test Requisition Form, start by downloading the category-specific TRF that matches the test you want to order, then complete the patient demographics, ordering provider details, test selection, ICD-10 diagnostic codes, and billing section. Pair the completed form with a signed informed consent, a properly labeled specimen, and any supporting clinical documentation, then submit the package through the GeneDx provider portal or by fax to (201) 421-2010.1GeneDx. Rapid and Ultrarapid Sequencing Test Requisition Form Most results come back in two to four weeks.2GeneDx. How to Order Genetic Testing from GeneDx
Pick the Right Form First
GeneDx does not use a single universal requisition. Instead, it publishes a separate TRF for each testing category: cytogenomics for chromosomal microarray and related tests, a dedicated form for rapid and ultra-rapid exome sequencing, and additional category-specific forms covering areas like neurology panels, cardiology panels, and hereditary cancer testing. The full set of PDFs lives on the GeneDx forms page, and the online test catalog is searchable by condition, gene, or clinical indication so you can confirm which form matches your order.3GeneDx. GeneDx Order Forms and Provider Documents Each catalog listing also notes recommended use cases, methodology, and sample requirements.2GeneDx. How to Order Genetic Testing from GeneDx
Using the wrong form routes the specimen into the wrong workflow. Verify the category before you start writing in fields.
Patient and Ordering Provider Information
The top of every TRF collects patient demographics: full legal first name, last name, date of birth, and sex assigned at birth.4GeneDx. Cytogenomics Test Requisition Form These identifiers have to match the specimen tube label exactly. A mismatch between the tube and the form is one of the most common reasons a sample gets flagged at intake.
Below the patient block, enter the ordering provider’s name, role or title, National Provider Identifier (NPI), and phone number. An optional field accepts a second ordering provider when a case involves more than one clinician. Check the NPI character by character. An incorrect number creates billing problems and can delay the release of results to the right clinician. You also select how you want the report delivered: fax, email, or the provider portal.4GeneDx. Cytogenomics Test Requisition Form
Test Selection and ICD-10 Codes
Each TRF has a section for the specific test or panel you are ordering. Reference the GeneDx test catalog for the correct test name and catalog code. The exact test name determines which genomic regions the lab sequences and analyzes, so this field is not a place for approximations.
Beneath the test selection, the form requires ICD-10-CM diagnostic codes supporting medical necessity. By signing the TRF, the ordering provider attests that the requested tests are reasonable and medically necessary.4GeneDx. Cytogenomics Test Requisition Form Blank ICD-10 fields or vague codes invite insurance denials and slow processing. Attach supporting clinical notes, a family pedigree, prior lab reports, or imaging summaries when you have them. The variant interpretation team uses that phenotypic context to assess whether a detected variant actually explains the patient’s symptoms.
Signed Informed Consent
GeneDx will not process a specimen without a signed informed consent from the patient or legal guardian. The consent document confirms that the individual understands the nature of molecular genetic testing, its potential risks and limitations, and their financial responsibility for testing ordered by their provider.5University of Rochester Medical Center. Informed Consent
For exome and genome sequencing, the consent also asks whether the patient wants to receive secondary findings, meaning medically actionable genetic variants unrelated to the primary reason for testing. You and the patient decide together during the consent conversation, and the choice is recorded on the form.6GeneDx. Secondary Findings in Genetic Testing The lab follows the ACMG secondary findings list, currently version 3.3, as the standard for which genes qualify.7PubMed. ACMG SF v3.3 List for Reporting of Secondary Findings in Clinical Exome and Genome Sequencing Family members tested alongside the proband record their own preference separately.
Specimen Collection and Labeling
The specimen type depends on the ordered test. Buccal (cheek) swabs are common across many panels. GeneDx buccal kits include a sponge swab and a transport tube prefilled with a tinted stabilizer solution. After collection, the specimen can sit at room temperature for up to one week (preferred) or up to 60 days at the manufacturer’s limit.8GeneDx. Specimen Requirements
Label the tube with the patient’s name plus a second identifier such as date of birth, specimen ID, or medical record number, and make sure every character matches the TRF. The lab rejects specimens when the stabilizer has leaked out of the transport tube or when the tube is missing either the name or the second identifier.8GeneDx. Specimen Requirements
One exception matters: buccal swabs are not accepted for patients who have received an allogeneic bone marrow or stem cell transplant, because cheek cells may carry donor DNA. For those patients, DNA from cultured fibroblasts is required.8GeneDx. Specimen Requirements Some tests also require blood drawn in EDTA tubes rather than buccal swabs, so check the catalog listing for the specific test you ordered.
Insurance and Billing Section
If the patient has insurance, complete the billing section with the carrier name, insurance ID number, and subscriber name. The form has fields for both primary and secondary insurance. When you have obtained prior authorization or a referral number, enter it in the designated field and attach a copy of the authorization letter. Having that paperwork in place from the start prevents billing disputes later.4GeneDx. Cytogenomics Test Requisition Form
Medicare covers next-generation sequencing under a National Coverage Determination, but only for specific situations. For hereditary cancer panel testing, the patient must have ovarian or breast cancer, a clinical indication for germline testing, and a relevant risk factor, and the test must use an FDA-approved or FDA-cleared platform. Medicare does not cover genetic testing for beneficiaries without a personal history of cancer.9Facing Our Risk of Cancer Empowered. Medicare Finalizes Genetic Testing Policy Local Medicare Administrative Contractors may issue their own coverage determinations for hereditary cancer testing beyond breast and ovarian cancer, so check with the applicable MAC if your patient’s situation falls outside the national policy.
For patients worried about cost, GeneDx runs a financial assistance program limited to U.S. patients, with eligibility based on household size, insurance type, and annual pre-tax household income. GeneDx does not publish fixed income thresholds. Patients use an online financial aid calculator to estimate their potential assistance level, and the estimate is not a guarantee.10GeneDx. Financial Assistance Program Run the calculator before specimen collection so the patient knows what to expect.
Submitting the Completed Package
The fastest route is the GeneDx online ordering portal. It is HIPAA-compliant and gives you an immediate confirmation once you submit. Paper TRFs remain available for providers who prefer not to use the portal.2GeneDx. How to Order Genetic Testing from GeneDx
If you are faxing, send the completed TRF, signed consent, and any supporting clinical documentation to (201) 421-2010.1GeneDx. Rapid and Ultrarapid Sequencing Test Requisition Form Confirm that every page came through legibly. A missing consent page or an unreadable ICD-10 code will trigger a callback from the lab.
When shipping a physical specimen, place a paper copy of the completed TRF in the external document pouch of the shipping container so technicians can match the sample to the electronic or faxed paperwork on arrival. Keep the TRF separate from the specimen itself. Use the pre-printed courier shipping labels GeneDx provides for tracked transport.
What Happens After You Submit
Once the specimen and paperwork arrive, you can track progress through the provider portal. Results are delivered securely through the same portal, typically within two to four weeks.2GeneDx. How to Order Genetic Testing from GeneDx Rapid exome sequencing is faster. The ExomeDx Rapid test delivers a provisional result within seven calendar days after testing starts, covering pathogenic and expected pathogenic variants that definitively explain the phenotype, with a full written report of all clinically relevant variants following in roughly two weeks.11GeneDx Provider Portal. ExomeDx Rapid, Proband
Most delays happen before sequencing even begins, caused by incomplete TRFs, missing consent forms, or specimen labeling errors that force the lab to call the ordering provider. Getting every field right on the first submission is the single most effective way to speed up results.